Aprotinin inhibits trypsin, chymotrypsin, plasmin and kallikrein with high activity.
Kininogens are cysteine proteases from the cystatin superfamily. Kininogenases split kininogens into kinins (inflammation mediators).
Activity: 1 PEU (Ph. Eur. Unit) corresponds to 1950 KIU (Kallikrein Inhibitory Units). 1 PEU corresponds to approx. 1.5 TIU (Trypsin Inhibitory Units). 1 TIU corresponds to approx. 1300 KIU.
Specific Activity: ≥3.0 PEU/mg corresponding to ≥5850 KIU/mg
Recommended end concentration: 1.54 µM (10 µg/ml).
pH-optimum: 7.0-8.0.
Appearance | white to off-white powder |
Specific activity | ≥3,0 PEU/mg equals ≥5400 KIU/mg |
pH value (aqueous solution) | 5,0-7,0 |
Loss on drying | ≤6 % |
Lyophilized from bovine lungs. |